Work that aims to bring together the results of all studies that address a particular research question. They provide a comprehensive and unbiased summary of the research.

For example, one clinical trial may not give a clear answer about the effectiveness of a treatment. This may be because the difference between the treatments being tested was very small, or because only a small number of people took part in the trial. So systematic reviews are used to bring the results of a number of similar trials together, to piece together and assess the quality of all the evidence. Combining the results from a number of trials (using meta‐analysis) may give a clearer picture. HTAI

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