A study to determine whether a treatment is safe and effective. It is carried out with a sample of intended patients, usually after laboratory studies and studies with healthy volunteers have been conducted. The trial is set up to answer one or more questions. For example, does the treatment cause adverse effects and, if so, how serious are these? Does the treatment result in desired outcomes for patients, and if so, how much improvement takes place? What is the safest dose to avoid serious adverse effects while still achieving the desired outcomes? HTAI
